Author: Stephanie Figon, MS, RDN, LD

Founder of NutriScape.NET. As a dietitian since 1992, Steph Figon has had experiences in consulting, 15 years in clinical, and has operated a private practice nutrition counseling office for since 2011. Connect on Linkedin

mTG: How Food Glue Can Be As Harmful As Gluten For People With Celiac And Might Even Be Part of the Cause

November 3, 2023

For people living with celiac, it is an unlabeled additive in food that may be as bad as gluten. For people without celiac, it may be partly responsible for the alarming rise in autoimmune disease. Microbial transglutaminase, or mTG, has been increasingly added to food over the past 30 years. It is known unappetizingly as “meat glue” because it gives hot dogs their unique texture, but it’s also used in many other foods. Read on to discover how this substance, which is FDA classifies as “Generally Recognized As Safe”, might have unrecognized side effects.

What Is mTG?

Transglutaminase is an enzyme found in many living things, and mTG is one type of this enzyme. It’s best known for creating a specific bond between amino acids in proteins. This bonding ability has led people to call it “meat glue.” Companies use mTG to improve the look, feel, and shelf-life of foods like meat, milk, and fish. It is even added to baked goods and sweets. mTG is also in other industries like beverages and oil, and even in health supplements.

One big reason companies use mTG is that it makes food last longer on store shelves. It’s a hot topic for food manufacturing, with many new patents being filed and mTG use expected to grow in the coming years. As for how much is used, up to 15 mg of mTG can be consumed in a day, and around 50-100 mg is needed to improve one kilogram of food.

Transglutaminase in the human gut comes from different places. Some of it is from the food we eat, like processed meat, cheese, yogurt, turkey roasts, and even in gluten-free baked goods. Other sources include probiotic supplements because mTG helps probiotic supplements survive the journey through the stomach to the lower intestines.

Our gut also has its own natural sources of the enzyme, coming from both good and bad bacteria, as well as yeasts and fungi. Finally, the cells lining our gut can also make transglutaminase. All these different sources mix together in the gut to modify proteins.

How Celiac Gets Started

In the initial development of celiac disease, it’s the gliadin portion of gluten that triggers the initial immune reaction. The enzyme tTG (tissue transglutaminase) modifies this gluten, making it more immunoreactive. After celiac disease is established, the body not only reacts to gluten but also to tTG. When someone with celiac disease eats gluten, the tTG enzyme modifies the gluten protein, triggering an immune response. The immune system then mistakenly targets not only the modified gluten but also the tTG enzyme itself, which is a natural part of the body. This is why antibodies against tTG can be used for diagnosing celiac disease. So, even though the initial reaction is to gluten, tTG’s interaction with gluten amplifies the immune response.

Why mTG Matters In Celiac

In celiac disease, the immune system mistakenly targets tissue transglutaminase (tTG). The tTG enzyme changes the structure of gluten, a protein found in wheat, rye, and barley. The modified gluten then becomes a target for the immune system, leading to inflammation and damage in the small intestine. This damage is what causes the symptoms and complications associated with celiac disease.

A big concern is the similarity of how mTG and tTG interact with gliadin, a component of gluten. Both tTG and mTG enzymes modify proteins, including gliadins.

They both create new complexes that trigger the immune system. This leads to the production of tTG antibodies that mark the beginning of celiac disease. When mTG treats wheat, it causes several immune responses.

The mTG enzyme acts like a copycat of the tTG enzyme that modifies gluten in a way that triggers celiac disease. This tTG (tissue transglutaminase) is the actual target of the immune attack in people with celiac disease. [PMC4502714]

Researchers believe that mTG and other common food additives increase intestinal permeability. Leaky gut results in the entry of foreign immunogenic antigens that activate the autoimmune cascade. [PMID: 25676324]

Anti-mTG… antibodies correlate with intestinal damage to a comparable degree as anti-tTg. 

Autoimmunity Reviews: The industrial food additive, microbial transglutaminase, mimics tissue transglutaminase and is immunogenic in celiac disease patients [PMID: 27640315]

How Microbial Transglutaminase Cross-Linked Complexes Might Cause Disease:

For people who do not have celiac, there is concern that mTG may lead to the development of the disease. [PMC8537092] Researchers cite the following reasons:

Immune Activation: Scientists used gold tagging to track gliadin and mTG through cells using electron microscopy. Both molecules move through cell compartments to the basolateral membrane. This location suggests these molecules interact with immune system cells to produce antibodies. The bonds formed by mTG and gliadin are stable and resistant to breaking down in the gut. This makes it even more likely that they’ll challenge the immune system.

Leaky Gut: Leaky gut might let things like bacteria, toxins, and even gliadin or gluten into the bloodstream. This can have an effect on the brain, possibly contributing to brain diseases and other conditions, including celiac disease. Additives in processed foods, along with certain enzymes, might also play a role in chronic diseases.

Increases Gliadin Uptake: The movement of gliadin peptides across the lining of the gut is helped by specific substances like secretory IgA and a receptor called apical transferrin receptor, especially when tTG (tissue transglutaminase) is present. Research shows that adding tTG to cells in a lab setting increases the uptake of gliadins. Since microbial transglutaminase (mTG) works similarly to tTG, it’s reasonable to think that mTG could also help gliadins enter the lining of the gut, which could make celiac disease worse. However, it’s not clear how mTG affects the barrier between the blood and the brain.

Suppression Protective Mucous Barriers: A healthy mucus layer in the gut helps keep harmful substances and bad bacteria away from the cells lining the gut. One key ingredient of this mucus is MUC2 mucin, which is a good target for the enzyme tTG (tissue transglutaminase). tTG modifies this mucin in a way that actually boosts its protective qualities. However, microbial transglutaminase (mTG) can mess with this mucin’s stability and make it easier for harmful substances to attach to gut cells. On the immune side of things, mTG from a specific bacteria, Streptococcus suis, hampers the ability of the immune system to engulf and remove harmful particles, weakening a key defense mechanism.

Contributes to Imbalances in The Gut Microbiome: Microbial transglutaminase (mTG) serves as a survival tool for microbes and also weakens gut immunity. For example, when scientists put the gene for mTG from one type of bacteria into another, Lactococcus lactis, the bacteria grew a lot more. Advances in bioengineering have made it easier and cheaper to produce this enzyme. The passage raises the question of whether bacteria that produce a lot of mTG could transfer this ability to other bacteria in the human gut, which could throw off the balance of the gut environment.

Potential Immune Activation: Certain immune cells in the intestine, like dendritic cells and macrophages, can interact with tissue transglutaminase (tTG). These cells can actually take in the enzyme. These immune cells might provide a new way for mTG and gliadins to come into contact with deeper immune cells in the tissue.

mTG Is Active Inside The Gut: Microbial transglutaminase, or mTG, forms complexes with gliadin that are resistant to the stomach’s digestive enzymes. mTG retains its activity up to 172°F (60°C) and remains active in environments with a pH of 4.0 or more. This can be significant because many individuals have reduced stomach acidity, either from eating, which temporarily neutralizes stomach acid, or due to the use of acid-suppressing medications. As a result, mTG might be active in various parts of the digestive system, forming complexes with gliadin that are tough and can stimulate an immune response.

To Dive Deeper

For those who are interested in the technical details, here’s more of a step-by-step breakdown of how mTG from processed foods affects your gut and immune system:

(A) When you eat foods like meat, fish, dairy, and bread that have been treated with mTG, this additive enters your digestive system.

(B) Inside your gut, mTG sticks to certain food particles, forming complexes.

(C) Proteins found in wheat, called gliadins, are easily bound by mTG, which can change them in a way that prompts an immune response. Not only that, but mTG can also come from other foods and microbes like yeast, leading to more binding and possible gut irritation.

(D) mTG might disrupt the protective mucus lining inside the gut, weakening the barriers that keep harmful substances out of your gut wall. If gluten is present, it can make this barrier even leakier, letting these complexes pass deeper into the gut lining.

(E) Once inside the deeper layers of the gut, these complexes can fire up the immune system, leading to inflammation. This involves various immune cells, like those that release signals to call more immune cells to the area, potentially causing more inflammation.

mTG Usage Should Be Labeled and Declared on Food Products

There are growing concerns about the use of microbial transglutaminase (mTG) in the food industry. Regulatory agencies, academic experts, and social media influencers are all issuing warnings. One key point is the call for transparency, requiring food products to declare the use of transglutaminase on their labels. This is particularly critical for those with celiac disease, as mTG can increase the immunogenicity of gluten. In countries like Switzerland, Germany, and Canada, the public has been notified about these safety concerns, and the enzyme must be labeled on the final product.

To Sum It Up

Microbial transglutaminase, a kind of “food glue,” has been used in food processing for about thirty years and its use is still growing. Although this enzyme is recognized as generally safe and is used to bind proteins together, it has some negative aspects that are often overlooked. It doesn’t have to be listed on food labels because it’s considered a processing aid, not an ingredient, which means it isn’t subject to strict safety testing. This enzyme can weaken the gut’s protective barriers and increase the risk of immune reactions and inflammation. It acts like some of our body’s own enzymes and might play a role in various long-term health problems. Authorities are being called to reevaluate how microbial transglutaminase is classified and to consider labeling it on food products and checking its safety more closely. Changes in these regulations could significantly alter food labeling and safety checks.

EMF

July 31, 2023

It Started With Microwave Syndrome

In the 1970s, during the Cold War, Soviet researchers noticed a set of health problems, termed “microwave syndrome”, among military personnel frequently using radio and radar equipment. These soldiers experienced symptoms such as chronic fatigue, dizziness, headaches, and sleep disturbances, seemingly linked to prolonged exposure to low-level electromagnetic fields (EMFs). This initial report led to ongoing global research into the potential health effects of EMFs, even influencing today’s discussions about the health impacts of modern technology, such as mobile phones and Wi-Fi devices. It underscores the need for continuous research as our technological environment evolves. [PMID: 32289567].

Then There Were CRT Computer Screens

In the 1980s, as computers became common in workplaces, workers in Sweden and Finland started reporting health problems. These issues included skin symptoms like flushing and tingling, along with headaches, dizziness, fatigue, and sensitivity to light. These symptoms were associated with prolonged use of cathode ray tube monitors. The Finnish identified this pattern of symptoms as electromagnetic hypersensitivity (EHS), potentially linked to exposure to electromagnetic fields (EMFs). Both Swedish and Finnish governments took these reports seriously, instigating research into the effects of EMFs on health and leading early efforts to manage potential occupational health risks associated with evolving technologies. This marked a crucial period in understanding the health implications of man-made EMFs.

What Are The Health Hazards Associated With EMF?

Electromagnetic fields (EMFs) are areas of energy that surround electronic devices. The World Health Organization (WHO) states that low-level EMF exposure produced by electronic devices poses minimal risk to human health. This is at the same time that 5G and smart meters are dramatically increasing our ambient exposure to EMF. High-level exposure may have health effects. Some health hazards associated with high-level or prolonged EMF exposure include:

  1. Depression and Anxiety: Some research indicates a connection between high levels of EMF exposure and mood disorders, though more research is needed. [PMID: 26300312]
  2. Cognitive Dysfunction: High-level exposure to EMFs may affect cognitive functions such as attention, memory, and problem-solving. More research is needed to substantiate these findings. [PMC9189734]
  3. Electromagnetic Hypersensitivity: Some people report a variety of symptoms that they attribute to EMF exposure. While these symptoms are real, it is currently unclear whether they are caused by EMF exposure or other environmental factors. [PMID: 32289567]
  4. Headaches: There’s limited evidence linking exposure to EMFs to headaches, although the research is not yet definitive.
  5. Cancer: There’s been extensive research on the link between EMF exposure and cancer, especially brain tumors. However, the findings are mixed, and the WHO’s International Agency for Research on Cancer (IARC) classifies EMFs as “possibly carcinogenic to humans,” highlighting the need for more research. [PMC5504984]

Problems Interpreting the Science

There is a fair amount of skepticism about the science surrounding EMF. One issue is the problem of studies prematurely declaring safety of EMFs on the basis of studies that seem as though they are specifically designed not to find an effect. This is evidenced by the very short duration of studies citing the safety of EMF. Then, there is the problem that any symptoms of the expected harmful effects would be very non-specific because of the nature of EMF damage. Current research also does not address the problem that one person may be much more sensitive than another. Therefore if EMF is only affecting 2 people out of the 10 people in the study, the effects on those 2 people are easily dismissed because the group as a whole did not have a statistically significant difference from the control condition. All these factors add together to make it a very difficult challenge for researchers to design studies that would pick up the subtle changes that might be related to EMF exposure.

It is difficult to get a man to understand something when his salary depends upon his not understanding it. 

Upton Sinclair-Author of The Jungle

As if this wasn’t problem enough, vague evidence and bias of scientific reviewers makes it even more challenging. There are unlimited amounts of money available from the telecom industry to fund organizations friendly to their cause. Their duty to make profits for their shareholders requires them to do all they can to shape the public narrative. Even agencies that are supposed to be objective in their interpretation of the science sometimes appoint scientific bodies that have clear and obvious industry bias. This was the case when WHO was widely criticized for its handling of appointments to a scientific review board. [PMC5504984]

Yet, even with all these difficulties in study design and interpretation, science is moving forward.

Diving Into The Science

Like in Multiple Chemical Sensitivity (MCS), repeated exposure to Electromagnetic Fields (EMFs) can cause hypersensitivity. Many hypersensitive people have a weak detox system that can’t cope with high-stress levels. EMFs can affect cell processes, increase harmful free radicals, and disrupt normal brain function. EMFs have the potential to cause variations in cellular calcium signaling pathways, stimulate free radical processes significantly, and excessively produce reactive oxygen species (ROS) in living cells.

Magnetite crystals, which come from polluted air, may also contribute to how EMFs affect the brain. [PMC49775] EMFs might cause symptoms related to the heart, skin, immune system, and blood vessels.

The conclusion drawn is that the mechanisms causing electrical hypersensitivity symptoms are biologically feasible, and a variety of organic physiological responses are triggered post-EMF exposure.

After EMF exposure, patients can have symptoms affecting their nervous system due to damage and heightened responses. Researchers conclude that we need better tests for EHS and lower exposure limits to protect against the effects of EMFs. [PMID: 32289567]

EMF and Cognitive Dysfunction

In a paper entitled: “Low-Intensity Electromagnetic Fields Act via Voltage-Gated Calcium Channel (VGCC) Activation to Cause Very Early Onset Alzheimer’s Disease: 18 Distinct Types of Evidence“, researchers lay out the evidence that EMF may contribute to serious levels of cognitive decline.

The author is concerned that smarter, more highly pulsed “smart” wireless communication may cause widespread very, very early onset AD in human populations.

Martin Pall, Professor Emeritus of Biochemistry and Basic Medical Sciencs, Washington State University

Electromagnetic fields (EMFs) from devices like cell phones and Wi-Fi can make the amount of calcium in our body’s cells increase. Some researchers think that too much calcium could be a cause of Alzheimer’s disease, as it could trigger damaging processes and inflammation. It seems like a harmful cycle between a protein linked to Alzheimer’s and calcium exists. Some studies suggest that EMFs could cause Alzheimer’s Disease, including cases that start early in life. Research in animals also shows that low-level EMFs can lead to brain damage similar to Alzheimer’s Disease. Interestingly, a moderate increase in cellular calcium from EMFs might also have protective effects. The author worries that new wireless technology might increase the risk of Alzheimer’s Disease, especially at an early age. [PMC9189734]

EMF Research on Depression And Anxiety

Electromagnetic fields (EMFs), like those from microwaves or Wi-Fi, work by activating certain channels called Voltage Gated Calcium Channels (VGCCs) that manage calcium in our cells. These channels are found all throughout our nervous system and are key for sending signals in our brains. Some researchers suggest that low-intensity EMFs can affect our mental health, causing symptoms of sensitivity. Studies show that EMFs cause changes in the brain and nervous system of animals, likely through the activation of VGCCs. This leads to an excessive release of brain chemicals and stress responses. In humans, certain genetic variations in VGCC activity have been linked to mental health changes.

Past studies done by the U.S. government found evidence that exposure to non-intense microwave EMFs in the workplace could cause a variety of mental health effects. Recent studies suggest similar effects from exposure to cell towers, excessive cell phone use, and wireless smart meters. Some symptoms reported include difficulty sleeping, headaches, depression, fatigue, difficulty concentrating, memory changes, dizziness, irritability, loss of appetite, restlessness, and changes in brain wave patterns.

The way microwaves and other EMFs work, their effects on the brain, past research, and several tests for determining cause-effect relationships all point to the possibility that various exposures to EMFs can cause a wide range of mental health effects. [PMID: 26300312]

EMF Effects on Headaches

Researchers reviewed 30 studies that had been done to determine whether cell phones were associated with headaches. They found that the odds of having a headache was 1.30 times higher for people who used mobile phones. The researchers then split the studies into groups based on the age of the people and how long they were exposed to the electromagnetic fields (EMF) from the phones.

They found that both age and exposure time affected the risk of headaches. They concluded that the age of the person and how long they were on the phone both influenced the risk of headaches. The longer someone used a mobile phone and the older they were, the more likely they were to have a headache. [PMID: 35064837]

Protecting Your Family From EMF

The complete elimination of EMFs is impossible due to their ubiquitous nature in our modern world. However, these steps can significantly reduce exposure, leading to a healthier living environment. Here are some practical steps families can take to reduce their exposure to electromagnetic fields (EMFs):

  • Limit the Use of Wireless Devices: Try to limit the time spent on wireless devices such as smartphones, tablets, and laptops. When not in use, switch them to airplane mode.
    • Turn Off Wi-Fi at Night: Turning off your Wi-Fi router at night can significantly reduce your EMF exposure.
    • Have Regular Screen-Free Times: Encourage activities that don’t involve screens, such as outdoor play, reading physical books, or board games.
  • Maintain Distance: Keep some distance between you and your electronic devices. Avoid carrying your cell phone in your pocket or sleeping with it next to your bed.
  • Use Wired Connections: Whenever possible, opt for wired connections. For example, use a wired phone for long conversations and a wired internet connection for your computer.
  • Choose Low EMF Devices: When buying new appliances, look for those that have been designed to emit lower levels of EMFs.
  • EMF Shielding: Consider EMF shielding products such as cases and covers for cell phones, tablets, and laptops.
    • Shielding Babies in Utero: Pregnant women, in particular, should be cautious about their EMF exposure. Consider wearing EMF shielding clothing during pregnancy, especially when in environments with high EMF, like near electronic devices or Wi-Fi routers. This type of clothing can help protect the developing fetus from potential harmful effects of EMFs.
    • Use Protective Canopies: EMF protective canopies can be used over beds to reduce exposure while sleeping.
  • Be Aware of Power Lines: If possible, avoid living near high-voltage power lines or cell towers.
  • Limit the Use of Bluetooth Headsets: Instead, use the speakerphone or wired earphones.

Products That Can Reduce Your EMF Exposure

There are several products available on Amazon that are designed to help shield against EMF. Here are a few:

EMF Radiation Meter

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EMF Blocking Faraday Fabric

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Land Line Phones

Old fashion phones with cords attaching them to the wall emit essentially no EMFs. On the other hand, a cordless phone connects to a base station that’s operating at low power 24-7. Cordless phones don’t emit as much EMF as cell phones. However, the base station of a cordless phone continually emits EMFs, even when the phone isn’t in use, leading to continuous exposure in the home. If you decide to keep your cordless phones, consider using a Faraday cloth to cover it to reduce your EMF exposure.

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Device Covers

Shop EMF Blocking Laptop Mat (Affiliate Link)
Shop EMF Blocking Covers For Smart Electrical Meters (Affiliate Link)

EMF Blocking Clothing

EMF Blocking Beanies and Hats (Affiliate Link)
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Blankets

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Pregnancy Belly Armor

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Device Covers

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Bed Canopies

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EMF Blocking Paint

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To Sum It Up

The discourse surrounding the potential dangers of electromagnetic fields (EMF) is laden with biased and conflicting scientific evidence, making it a complex and contentious issue. Some studies highlight the possible health risks associated with EMF exposure, ranging from sleep disturbances to more severe neurological effects, while others refute these claims.

Amidst this scientific uncertainty, EMF shielding remains a practical approach for anyone concerned about potential EMF-related health issues. Using the available shielding methods to minimize exposure may provide peace of mind and an extra layer of protection against the unknown and debated effects of EMF. Though the definitive risks of EMF remain a subject of ongoing research and debate, taking precautionary measures reflects a practical response to the existing body of evidence.

Notice: The NutriScape.NET site is intended for educational purposes and does not constitute the practice of health care advice, diagnosis, or treatment. Individuals should seek the advice of a qualified healthcare provider for any questions regarding personal health or medical conditions. Access to independently licensed Registered Dietitian Nutritionists can be found through our Telenutrition site.

Journey to Motherhood: Your Comprehensive Guide to Pre-Pregnancy Detox Preparation

July 19, 2023

Welcome to a journey that focuses not only on the miracle of life, but also on your wellbeing as a soon-to-be mother. Preparing your body for pregnancy isn’t only about prenatal vitamins and tracking ovulation cycles—it’s also about creating the healthiest environment possible for your growing baby. A key part of this preparation involves minimizing the toxic burden on your body and reducing your exposure to xenoestrogens.

This might sound daunting, but there are practical and manageable steps you can take to reduce your exposure to these unwanted chemicals and detoxify your body. As you embark on this beautiful journey towards motherhood, we offer this guide to help you improve your health, detox your body before pregnancy and provide the most nurturing environment for your tiny inhabitant. Let’s dive in!

The Problem

Sounding The Alarm: Why It Pays To Be Careful What You Eat and Drink

Few healthcare providers are aware that our water and food supply is full of chemicals of all kinds. Estrogen from birth control pills is excreted through urine and enters the water supply in cities. Forever chemicals never break down and they are everywhere in our environment. These chemicals are causing changes in the genitalia of amphibians and reptiles. When an effective dose is possibly as little at 2 drops in an Olympic size swimming pool, many scientists are worried. Forever chemicals are found in a range of everyday products from non-stick pans to water-resistant clothing and grease-resistant food packaging like popcorn bags and pizza boxes.

They can easily enter our bodies and have been detected even in the womb, crossing the placental barrier to reach the developing child. Xenoestrogens, a specific type of these chemicals, mimic estrogen in the body and can disrupt hormonal balance at critical periods during the development of the baby’s sex organs and brain. The presence of these compounds in cord blood makes scientists wonder if these chemicals are responsible for the skyrocketing rates of everything from autoimmunity to gender dysphoria. The extreme sensitivity of babies at various stages in utero makes the efforts to reduce our exposure all the more critical.

Your Liver Will Automatically Detox Your Body (But Only When Given The Right Nutrients)

Detox is poo-hoo’d by many, even those in health-care. It has this bad name because of the many charlatans selling diarrhea inducing high priced supplements that don’t address anything to do with toxins. Here’s the real story, and it is eye-opening. Although there is a tremendous amount of stuff going on in the image below, here’s what you want to know.

  • Your liver begins detoxifying by first turning toxins into substances that are even more toxic. Once Phase 1 is complete, there’s a possibility that Phase 2 detoxifications move more slowly than Phase 1, allowing toxic intermediary compounds to build up.
  • Your liver won’t detoxify anything unless you feed it the right nutrients.
    • Phase 1 liver detoxification will not work adequately without Vitamin B2 (riboflavin), B3 (niacin), B6, Folic acid, and B12, glutathione, and those colorful substances in fruits and vegetables known as flavinoids.
    • Phase 2 liver detoxification requires magnesium, cysteine, glycine, taurine, glutamine, choline and glutathione. And it requires Vitamin B5, Folic Acid, and B12.
  • The “Standard American Diet” does not provide adequate nutrients to carry out detoxification processes.
    • Fiber: There is not enough fiber to bind bile acids and toxins to take it out of the body through the digestive tract.
    • Water: There’s not enough water to make optimal quantities of urine needed excrete waste compounds.
    • B Vitamins: The B vitamins required for these reactions are used up by stress, alcohol consumption, a high-sugar diet, pregnancy and lactation, certain medications, age, physical activity, and smoking.
    • Magnesium: More than half the population is failing to get adequate magnesium to support Phase 2 Detoxification.
    • Weed Killer: Glyphosate slows down Phase 1 detoxification by inhibiting the cytochrome P450 enzymes. Non-organic wheat, soy, and produce are covered with glyphosate. Researchers say: “Glyphosate’s inhibition of cytochrome P450 (CYP) enzymes is an overlooked component of its toxicity”. Bread is specifically high in glyphosate due to farmers spraying glyphosate directly on wheat to dry it out days before harvest.
Liver Detox Pathways

Step 1: Stop Taking In Toxins

Organic Foods

Studies show lower rates of infertility, birth defects, allergic sensitisation, ear infections and metabolic syndrome in those with habits of long-term organic food choices. [PMC7019963]

The nutrient content of produce can vary depending on the farming methods used and yearly conditions. However, analyses of various studies have consistently shown that organically grown foods generally contain higher levels of vitamin C, iron, magnesium, and phosphorus compared to their non-organic counterparts. Not only are these foods richer in essential nutrients, but they also contain fewer nitrates and pesticide residues.

Organic foods are also noted for having higher concentrations of key antioxidant phytochemicals such as anthocyanins, flavonoids, and carotenoids. Laboratory studies have consistently shown that organic fruits and vegetables have enhanced antioxidant activity and are more effective at blocking the mutation-causing properties of toxic compounds. Furthermore, some health advantages have been linked to consuming organic dairy products, such as a reduction in allergic dermatitis symptoms. [PMID: 20359265]

The Dirty Dozen And The Clean 15

Some foods should only be bought in their organic form, like bread. Produce is more variable in its chemical content so buying organic matters more with some types of produce than others. The Environmental Working Group has studied this question for many years and has created their trademarked “dirty dozen” and “clean fifteen” lists to help us keep things strait. Visit the Environmental Work Group at ewg.org to learn about their wide ranging work. The buttons that follow allow you to visit their dirty dozen and clean fifteen lists directly and sign up for their newsletters so that you can get ongoing help in clearing toxins from your life.

The Dirty Dozen On EWG.org
The Clean 15 on EWG.org

Soap, Body Lotion, Shampoo: Toxins Everywhere

Use the EWG’s Skin Deep Product Lookup. The Think Dirty App is a useful app for your phone that allows you to look up products by their barcodes for convenience. However it’s important to recognize the potential for bias in this app, which has been criticized for creating partnerships with brands.

Skin Deep Product Lookup

Getting Rid Of The Non-Stick Pans

“Teflon” and non-stick pans were historically made with perfluorooctanoic acid (PFOA), a chemical linked to various health problems. The problem is that these chemicals stay in the body for a long time. Also, Teflon-coated pans can release harmful fumes when heated. But despite recent production changes, health concerns persist around non-stick cookware. For women who will someday become moms, it can never be too early to leave behind the non-stick cookware. Alternatives like stainless steel, cast iron, and ceramic cookware offer a safer option.

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Shop Stainless Cookware

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Household Cleaners Are A Source of Toxins

When you smell a fragrance, think of phthalates! Fragranced household cleaners commonly contain phthalates, known endocrine disruptors that can interfere with hormonal systems. Triclosan is an antimicrobial agent present in many antibacterial products. It can disrupt hormone function and contribute to antibiotic resistance. Manufacturers use alkylphenol ethoxylates (APEs) in laundry detergents and all-purpose cleaners, and these nonylphenol ethoxylates (NPEs) can interfere with hormones and are linked to various health issues.

Polishing agents for bathroom fixtures, sinks, and jewelry often contain ammonia, which can trigger respiratory issues and skin irritation. Chlorine bleach, a potent disinfectant and whitener, may harm the lungs and skin and can create dangerous gases when mixed with ammonia. Volatile organic compounds (VOCs) also exist in a wide array of cleaning products and can trigger a range of health problems from headaches to liver and kidney damage.

It’s time to check under the sink and decide what to keep and what to toss. Once again, the Environmental Work Group has put together a tremendous set of resources for looking up product safety. Check it out:

Search 2500 Cleaning Products on EWG

Non-toxic alternatives for household cleaning are a smart and sustainable choice. For example, a simple mix of vinegar and water can make an excellent all-purpose cleaner for countertops and windows. Baking soda serves as a powerful scrubbing agent for tough stains and can also freshen up carpets and rugs when sprinkled on, left for a few minutes, and then vacuumed up. Hydrogen peroxide can replace bleach for whitening and disinfection. Essential oils, like tea tree, lemon, and lavender, can add natural fragrance to homemade cleaners while also offering antimicrobial properties. Castile soap is a versatile, vegetable-based product that can be used for a range of cleaning tasks, from washing dishes to mopping floors.

How Pure is Your Water?

After lead from the water supply poisoned thousands of children in Flint Michigan, many people woke up to the fact that there are plenty of places that the water is unsafe. This issue is particularly acute in older cities with outdated plumbing systems. The second major concern is runoff from agricultural activities that introduce pesticides, herbicides, and fertilizers into the water sources. Atrazine is a common agricultural herbicide that is detected in water supplies due to runoff from farming activities. Studies have linked exposure to atrazine to preterm birth or low birth weight. Then, there are industrial pollutants and microplastics that find their way into the water supply.

These issues are widespread, so it pays to check on whether your water is safe. If you have your own well, you will want to think about the agricultural runoff. If you have city water, you’ll be able to look up your water quality by zip code. Once again, EWG has provided the resource:

Is Your Tapwater Safe? Search By Zip Code on EWG

If you find your water is not pure, a Guide To Water Filters is available on EWG.org as well. Whatever filtration system you choose, you make sure it is certified by the Water Quality Association or NSF.

Consider The Possibility of Lead

There are a lot of ways that a person can be exposed to lead aside from lead pipes causing water contamination. For example, if you live in a home that was built before 1978, there’s a high likelihood that it was painted with lead-based paints. Think about whether you have ever refinished old painted furniture that may have been painted with lead paints. Have you ever been involved in soldering with lead, such as in stained glass, of plumbing.

Crops can be contaminated with lead if they are grown in contaminated soil. Lead particles from leaded gasoline or paint can settle in the soil and remain there for years. Root vegetables like carrots, potatoes, and radishes, as well as leafy green vegetables, are especially prone to lead contamination. Therefore, washing vegetables thoroughly and peeling root vegetables can help reduce lead exposure.

It’s important to test any imported goods that might contain lead. These include toys, jewelry, cosmetics such as lipstick, and ceramics. The glazes used on some of these items may contain lead. Furthermore, some imported spices and foods have been detected to contain high levels of lead, and certain traditional remedies and cosmetics may also contain this harmful element.

Lead Testing

Lead tests check for harmful lead in your home. This is important in older homes with older homes built before 1978 when lead paint was finally banned. Lead is also present in some ceramic glazes, so don’t assume that the beautiful handmade ceramic coffee mug is safe. If someone got the glazes mixed up, it can contain significant amounts of lead.

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Step 2: Testing

Labs To Learn Your Own Toxin Status

The purpose of pre-pregnancy toxin testing is to prevent the possibility of accidentally exposing your baby to toxins from the moment of conception throughout the most vulnerable stages of development in utero. The alarming truth is that the vast majority of chemicals in use today have had very little safety testing before entering the marketplace. We are in a population-wide experiment with these chemical exposures. At the same time, epidemiologists are seeing alarming increases in rates of autism, ADHD, and chronic diseases of all types.

Unless your parents and you have been exceedingly careful since childhood about what you have been exposed to, you may look back on a long history that might include microwaving food in plastics, breathing in household chemicals, scented air fresheners, questionable water, chemical laden stain-proof carpets, paint fumes, grocery store receipts and tatoos. Certain occupations are known for very high exposure risk.

If you are armed with the knowledge of your specific toxin status, you can give a sigh of relief, knowing you are safe, or work with your healthcare provider to take steps to clear the toxins from your body. There’s really no way to know what all you have floating around in your system unless you test your levels. Although these tests might be considered expensive by some standards, they are worth the investment. Future health problems can be far more costly to your family over the many years to come.

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Total Tox-Burden

Vibrant Wellness		URINE. The Total Tox-Burden panel contains the Environmental Toxins, Mycotoxins, and Heavy Metals tests. The Environmental Toxins profile screens for the presence of 39 toxic substances in your body. The Mycotoxins profile helps identify the presence of mycotoxins, toxic substances produced by certain types of fungi, in your body. The Heavy Metals profile identifies if you have been exposed to toxic levels of heavy metals. ReportOrder Total Tox-Burden Test
Total Tox-burden + Organic Acids

Vibrant Wellness		URINE. The panel combines the Environmental Toxins, Mycotoxins, Heavy Metals, and Organic Acids tests. The Environmental Toxins profile screens for 39 toxic substances in your body. The Mycotoxins profile helps identify the presence of mycotoxins, toxic substances produced by certain types of fungi, in your body. The Heavy Metals profile identifies if you have been exposed to toxic levels of heavy metals. The Organic Acids test measures the levels of certain organic acids in your body. ReportOrder Total Tox-Burden + Organic Acids Test
Total Tox-Burden + PFAS Chemicals

Vibrant Wellness		URINE. The Total Tox-Burden panel contains the Environmental Toxins, Mycotoxins, and Heavy Metals tests. The Environmental Toxins profile screens for the presence of 39 toxic substances in your body. The Mycotoxins profile helps identify the presence of mycotoxins, toxic substances produced by certain types of fungi, in your body. The Heavy Metals profile identifies if you have been exposed to toxic levels of heavy metals. ReportOrder Total Tox-Burden + PFAS Test
NutriPro + Total Tox

Vibrant Wellness		SERUM, URINE, WHOLE BLOOD, Phlebotomy required. This panel combines the NutriPro, Environmental Toxins, Mycotoxins, and Heavy Metals tests. It can help identify nutrient imbalances and toxin exposure. ReportOrder NutriPro + Total Tox Test

Step 3: Clearing Toxins From Your Body

Sweating It Out: Clear Some Toxins With a Sauna

The skin is your body’s largest organ, and it does more than just cover you up. We often think nothing can get through it, but that’s not true. Think medication patches. It’s not just a one-way street, either. Your skin can also get rid of stuff your body doesn’t need. This includes toxins, which your skin can push out. That requires sweating, whether it’s being outside in a warm climate, exercising, hot yoga, or by taking a long hot bath. Sauna is a very practical way to accomplish toxin excretion above and beyond what you can achieve with urine and bile.

Many people avoid sweating whenever they can. We recommend the opposite strategy. Engaging in activities that stimulate sweating, such as exercising or using a sauna, can help your body naturally detoxify itself. Turning off your air conditioning in the summer may help, not only in sweating out toxins but in cutting your utility bills as well. Sweat is not just composed of water; it also contains a variety of waste products and toxins that your body is trying to eliminate. These can include:

  • Heavy Metals: Some studies have found that sweat can contain traces of heavy metals like lead, mercury, cadmium, and arsenic. These harmful substances can accumulate in the body from environmental exposure and are linked to all kinds of health problems.
  • Bisphenol A (BPA): This endocrine-disrupting chemical can be excreted through sweat. Research has shown that BPA can lead to health problems, including neurological effects, heart problems, harm to the immune system, and certain types of cancer. But don’t buy BPA Free plastics either, because manufacturers of BPA Free plastics are usually substituting other potentially toxic, but less well understood chemicals. Unfortunately, the only safe choice is to get rid of every plastic exposure you can. Glass doesn’t leach chemicals.
  • Phthalates: Used as plasticizers in many products from personal care items to vinyl flooring, phthalates are endocrine disruptors that can be eliminated via sweating.
  • Polychlorinated Biphenyls (PCBs) and Polybrominated Diphenyl Ethers (PBDEs): These are types of persistent organic pollutants (POPs) that have been used in various industrial and chemical applications. They can accumulate in the body over time and be excreted through sweat.
  • Ethylhexylglycerin: This is a common synthetic compound used in personal care products and can be eliminated via sweat.
  • Volatile Organic Compounds (VOCs): These are a group of chemicals used widely in industry and found in many household products. Some VOCs can be excreted from the body through sweat.

While sweating can help remove these toxins, it’s important to note that the primary organs for detoxification in the body are the liver and kidneys. Sweating is just one of the ways your body can help eliminate toxins. Maintaining a balanced diet, staying hydrated, and getting regular exercise can also support your body’s natural detoxification processes.

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Nutrition Strategy For Optimal Toxin Clearance

Before we dive into the details, here are your top detox strategies in a nutshell. A healthy diet plays a crucial role in supporting our body’s natural detoxification processes. Here are some strategies:

  • Hydrate: Water supports kidney function, one of our primary detoxification organs. Dehydration means toxins will tend to stay in the bloodstream longer. Divide your weight in pounds by 2 and that’s the number of ounces of water you will need as a basic rule.
  • Eat a Balanced Diet: Consuming a variety of fruits, vegetables, lean proteins, and whole grains will usually provide most of the nutrients needed for your body to effectively process and eliminate toxins. The problem is that it’s too easy to order a pizza, drink a few glasses of wine, and have desserts or sweetened beverages.
  • Limit Processed Foods: Highly processed foods often contain additives and preservatives that can be challenging for the body to process.
  • Include Fiber: Dietary fiber can help you eliminate waste by binding toxins to fiber as they pass through the gut. That way the toxins leave the body through the digestive tract rather than being reabsorbed into the bloodstream. You’ll need 25-35 grams of fiber per day. These are present in high-fiber vegetables and flax or chia seeds as well as whole grains.
  • Incorporate Detox Supporting Foods: Certain foods are known to support the body’s detox processes. These include cruciferous vegetables like broccoli and Brussels sprouts, garlic, berries, and foods rich in antioxidants. But don’t miss out on the detox food with 50 times the sulforaphane of the cruciferous vegetables: Broccoli Sprouts.
  • Limit Alcohol: Excessive alcohol can overburden your liver, an organ critical to the body’s detoxification processes.
  • Prioritize Gut Health: A healthy gut supports detoxification. Foods rich in probiotics, such as yogurt and fermented foods, can promote a healthy gut microbiome.

Nutrients That Help With Detoxification

There are several nutrient supplements that can support the body’s detoxification process:

  • B Vitamins: B vitamins, especially B6, B12, and Folate, are important for the phase 1 and phase 2 detoxification processes in the liver.
  • Glutathione: This is the body’s “master antioxidant”, which means it processes free radicals into harmless compounds. It also plays a vital role in recycling other antioxidants in the body and is essential for immune function and detoxification processes. Glutathione is made mostly in the liver and is made from the amino acids glutamate, glycine and cysteine.
    • N-acetyl cysteine (NAC): This supplement is an easily absorbed form of the amino acid cysteine. Cysteine is needed as a building block of glutathione, and can therefore help increase the body’s glutathione levels so that there is a greater capacity to detoxify.
    • Alpha-Lipoic Acid (ALA): This compound helps regenerate glutathione in the body, supporting detoxification.
  • Supplements for Liver Health:
    • Milk Thistle: This herb is often used to support liver health, as it’s believed to protect the liver from toxins and help it repair itself.
    • Dandelion: Traditionally used as a liver tonic, dandelion may help enhance the liver’s ability to process toxins and support overall liver function.
    • Artichoke Extract: It is believed to stimulate bile production and promote both liver and gallbladder function, helping the body to eliminate toxins.
    • Schisandra: An adaptogenic herb, schisandra is believed to have liver-protective properties and assist with the body’s stress response.
  • Probiotics: These can support the gut and its role in detoxification. They help maintain a healthy balance of good bacteria in the gut.
  • Minerals:
    • Magnesium: Important for many bodily functions, magnesium can also aid in detoxification by supporting liver function and the removal of toxins.
    • Selenium: This essential mineral helps boost the antioxidant capacity of the body, aiding in detoxification.
    • Zinc: This essential mineral is critical for maintaining a healthy immune system and may assist in heavy metal detoxification.
  • Fiber: Most fibers will bind toxins while they move through the digestive tract. This allows them to be taken out of the body rather than being absorbed. Some fibers are soluble, making a gel that surround the toxin.
    • Psyllium Husk: High in fiber, psyllium husk helps to support healthy bowel movements, which is a crucial part of the body’s natural detoxification process.
  • Toxin Binders:
    • Chlorella: This is a type of algae that binds to heavy metals in the body, aiding in detoxification.
    • Activated Charcoal: Activated charcoal is often used in acute poisoning cases due to its ability to bind to certain toxins and prevent their absorption in the body.
    • Bentonite Clay: This clay has been used for centuries to help remove toxins from the body when ingested or used on the skin.
  • Turmeric (Curcumin): Curcumin, the active component in turmeric, is known for its anti-inflammatory and antioxidant properties. It can help stimulate bile production in the liver, assisting in the body’s detoxification process.
  • Green Tea: Full of antioxidant compounds, green tea may assist in protecting the body from harmful toxins and support liver function.
  • Garlic: Garlic contains sulfur compounds that are known to assist in detoxification processes.
  • Spirulina: This blue-green algae is rich in vitamins and minerals and is believed to help remove heavy metals from the body.
  • Beetroot: Beetroots are high in antioxidants and other beneficial compounds that support liver detoxification processes.
  • Ginger: This root is thought to stimulate digestion and circulation, two processes that contribute to effective detoxification.
  • Cilantro: Some research suggests cilantro may help remove heavy metals from the body.

To Sum It Up

Preparing for pregnancy involves more than just the typical prenatal care—it’s also about ensuring a toxin-free environment for your baby to develop. From chemicals and heavy metals in our food and water, to the pollutants in the air, our daily lives are filled with potential exposure to toxins. But by adopting a proactive approach—minimizing exposure, testing for common contaminants, and utilizing a detoxification plan—you can help safeguard your health and that of your future child.

The journey might seem overwhelming at first, but every step taken towards reducing toxin exposure and enhancing detoxification is a step towards a healthier pregnancy. Lifestyle changes and nutritional supplements can play a crucial role in this journey. They should be implemented under the guidance of healthcare professionals. By focusing on your well-being as a mother, you’re setting the stage for a healthier, happier pregnancy and laying a strong foundation for your child’s future health.

Notice: The NutriScape.NET site is intended for educational purposes and does not constitute the practice of health care advice, diagnosis, or treatment. Individuals should seek the advice of a qualified healthcare provider for any questions regarding personal health or medical conditions. Access to independently licensed Registered Dietitian Nutritionists can be found through our Telenutrition site.

Breast Thermography: A Better Technology in Early Breast Cancer Detection

July 17, 2023

In recent years, medical science has taken giant leaps in the realm of cancer treatment. Yet, screening with mammograms hasn’t changed in years. Some are asking why women are willing to sit and wait for enough time to pass to allow cancer to get large enough to be seen on a mammogram. Another technology, thermal imaging for breast cancer detection has been available for decades for much earlier detection of breast cancer. Thermography is a non-invasive and radiation-free method that presents a potentially groundbreaking shift in our approach to breast health.

Breast thermography leverages the heat radiating from the body to identify abnormal patterns and physiological changes, which can be early signs of cancer. Unlike mammography, which primarily detects physical changes, breast thermography identifies functional changes within the breast. Thermography literally sees the heat caused by the inflammation present when cancer is in the earliest stages of development. Mammography waits for the cancer to become large enough to be seen on X-Ray.

This video explores the science behind breast thermography, its potential benefits, limitations, and how it could revolutionize breast cancer screening in the years to come. There are promising possibilities that this technology could contribute to improving early detection and ultimately saving lives.

Breast Thermography for Breast Cancer Screening

This video gives tremendous insight into what is involved in breast thermography for breast cancer screening.

Mammography vs. Thermal Imaging for Breast Cancer Detection: Weighing the Pros and Cons

When it comes to finding early breast cancer early, both thermal imaging and mammography have their unique advantages and potential disadvantages. And, while no one is advocating dropping the recommended screening mammograms just yet, there are many women at high risk who want greater reassurance than what routine mammograms can provide. And yet, aren’t all women at high risk when 1 in 8 women will develop breast cancer? Understanding these can provide valuable insights and inform your healthcare decisions.

The mammography industry is powerful, and no doubt, there are financial interests at play that are affecting the implementation of these technologies. An FDA article was written to warn consumers that thermal imaging is not a substitute for mammograms. Meanwhile, a scientific article states, “This method shows high accuracy and is a cost-effective form of diagnosis.” [PMC9731505]. That article also predicts that thermal imaging sensor technology is advancing and interpretation will continue to improve with the addition of AI to read images more accurately.

Advantages of Thermal Breast Imaging For Breast Cancer Screening:

  • Non-invasive and contact-free, unlike mammography which uses physical compression of the breast.
  • Radiation-free, providing a safer alternative to methods that expose the patient to radiation, such as mammography.
  • Capable of finding physiological changes related to increased blood flow and metabolism, potentially identifying early-stage tumors even before physical changes become apparent.
  • Thermal breast imaging is appropriate for women of all ages, including those under 40, who are typically not advised to undergo routine mammograms.

Disadvantages of Thermal Imaging In Breast Cancer Screening:

  • Not considered a standalone test for breast cancer screening. Thermal breast imaging is usually used in combination with other tests as it detects physiological changes rather than structural changes.
  • Can result in false positives (finding changes that aren’t cancer) or false negatives (missing cancers), raising questions about its sensitivity and specificity.

Advantages of Mammography:

  • Mammography is considered the gold standard for breast cancer screening because it is capable of detecting tumors that are too small to be felt.
  • Widely accepted, accessible, and covered by most insurance plans.

Disadvantages of Mammography:

Effectiveness is lower in women with dense breasts, where detecting cancer can be more challenging.

  • Exposure to even the low levels of radiation in a mammogram are known to poses risks.
  • Can cause physical discomfort or pain due to the breast compression involved in the procedure.

It goes without saying that a healthcare provider should be consulted when deciding the best breast cancer screening strategy for you based on your individual risk factors and health history. Both mammography and thermal imaging have their places in overall breast health management.

Your Risk May Factor Into Your Breast Screening Strategy

Some women are at far greater risk for breast cancer than others. Here are is a list of risk factors you should consider:

  • Age: The risk increases with age, with most cases diagnosed in women over 55.
  • Genetic mutations: Inherited mutations in certain genes, like BRCA1 and BRCA2, greatly elevate risk.
  • Family history of breast cancer: Having a close relative with breast cancer can increase risk.
  • Personal history of breast cancer: Women who’ve had breast cancer before are more likely to get it again.
  • Dense breast tissue: Dense breasts can both increase risk and complicate cancer detection.
  • Certain reproductive factors: Early menstruation (before age 12), late menopause (after 55), late childbirth, or never having given birth can raise risk.
  • Race and ethnicity: White women are slightly more likely to develop breast cancer than African American women, but African American women are more likely to die from the disease.
  • Exposure to estrogen: Extended exposure to estrogen, whether via hormone replacement therapy or certain reproductive patterns, can increase risk.
  • Obesity: Being overweight or obese, particularly after menopause, can increase risk.
  • Physical inactivity: Regular physical activity can help reduce breast cancer risk.
  • Alcohol consumption: The more alcohol consumed, the higher the risk.
  • Radiation exposure: Exposure, particularly before age 30, can increase the risk of breast cancer.
  • Oral contraceptives: Certain oral contraceptives may slightly raise breast cancer risk.
  • Root canals: Some research suggests a link between root canals and increased breast cancer risk, but this is controversial and not universally accepted in the medical community.

To Sum It Up

In critical health screenings for breast cancer detection, both mammography and thermal imaging play pivotal roles. Each technique offers unique advantages and presents potential limitations. There isn’t a one-size-fits-all approach to breast health.

Mammography still holds its place as the widely accepted standard for breast cancer screening. However, we cannot overstate the potential thermal imaging has, particularly for high-risk women, to enhance early detection efforts. It’s non-invasive, radiation-free nature, and has the potential to identify physiological changes before they become structural ones. This makes it a promising complement to traditional mammography, particularly for younger women and those with denser breasts.

The decision on which method to use should always be made in consultation with a healthcare provider. Your provider can help you consider your individual risk factors, overall health, and personal comfort. The goal is to ensure the most effective and comprehensive approach to breast cancer screening.

If we want to advance in catching the most aggressive forms of breast cancer in their earliest stages, it’s clear that a multi-faceted approach using both traditional mammography and thermal imaging will help.

Notice: The NutriScape.NET site is intended for educational purposes and does not constitute the practice of health care advice, diagnosis, or treatment. Individuals should seek the advice of a qualified healthcare provider for any questions regarding personal health or medical conditions. Access to independently licensed Registered Dietitian Nutritionists can be found through our Telenutrition site.

Can Gray Hair Be Reversed? Anecdotal Reports From People Taking NMN

July 5, 2023

Gray hair is a common sign of aging, but recent anecdotes from people taking NMN seem to suggest that it might be possible to reverse this process. Nicotinamide Mononucleotide (NMN), a supplement gaining attention in the field of anti-aging, has shown potential in restoring natural hair color. This surprising effect is linked to NMN’s role in enhancing cellular health by raising NAD+ levels. While it’s still early days, the possibility of using NMN supplements to battle the graying process is an exciting prospect. Think of it–no need to color!?

We share this video discussing telomeres, stem cells, and melanocytes. If you decide that NMN is interesting, follow the link to find out more.

Learn More and Order NMN Supplements

Nickel Allergy: Unveiling the Hidden Danger in Everyday Items

June 26, 2023

a chunk of nickel metal, the cause of Nickel Allergy.

Systemic Nickel Allergy Syndrome (SNAS) and Nickel Allergy might seem like obscure health concerns, for those affected, they aren’t trivial. These twin perils emerge when our bodies misidentify the common metal nickel as an enemy, setting off an array of serious symptoms that can disrupt everyday life. From skin rashes and swelling to digestive troubles and debilitating migraines, the physical toll can be significant. The psychological impact, too, is far from negligible, as the ever-present risk of a severe allergic reaction can breed a sense of unease and anxiety. In this article, we aim to shed light on these under-recognized conditions, demystifying their symptoms, causes, and treatment, and offering practical strategies to reclaim control over your health.

Unmasking the Culprit: What is Nickel and Where is it?

Let’s begin by identifying the villain of our story – Nickel. Nickel is a naturally occurring element, a metal that can be shiny and silver or a bit dull depending on its form. It’s everywhere around us and inside many of the objects we touch daily. You’ll find nickel in items like jewelry, coins, keys, eyeglass frames, zippers, cell phones, and even laptops. It’s used frequently because it’s durable, resistant to corrosion, and can create alloys with other metals for various purposes.

In your kitchen, you’re likely to find nickel in stainless steel utensils, pots, pans, and even some food items. Foods such as cocoa, nuts, oatmeal, and certain types of fish can have higher levels of nickel. While in most cases, this wouldn’t pose a problem, for people with nickel allergy, even these minute amounts can lead to discomfort.

Nickel also makes its way into our water supply. It can be found in tap water, primarily due to the nickel-containing pipes and fittings used in our plumbing systems. Though the concentrations are usually small, individuals with extreme sensitivity may experience symptoms upon consuming water with higher nickel content.

But wait, there’s more! Nickel can also be found in some everyday personal items like cosmetics, hair dyes, and even certain soaps. Nickel salts are sometimes used as ingredients in these products, which can cause problems for those with a nickel allergy.

In summary, nickel is quite the sneaky villain, blending seamlessly into our surroundings and day-to-day lives. Now that we’ve unmasked it, the next step is understanding how it impacts those with SNAS and nickel allergy.

Decoding SNAS: Understanding the Condition’s Impact on Your Body

If you have a nickel allergy and suffer from SNAS, your body might seem like a mystery. So, let’s delve into the science behind it in simple terms.

SNAS is a complex condition where your immune system, your body’s defense system, mistakes nickel, an ordinary metal, for an intruder. It’s like setting off a fire alarm when someone’s just burning toast – an overreaction that can cause more harm than good.

As the immune system swings into action, it triggers an inflammatory response. This is your body’s way of protecting you from what it thinks is harmful. But in this case, it causes discomfort and a range of physical symptoms. These can range from digestive issues like nausea, bloating and diarrhea, to skin rashes and intense itching. It can feel like your body is at war with itself, causing a lot of distress.

The biggest challenge with SNAS is its unpredictability. Some people experience mild discomfort, while for others, symptoms can be severe and disabling. It can also mimic other conditions, leading to misdiagnosis. But don’t despair – once correctly diagnosed, there are strategies to manage SNAS and minimize its impact on your life.

Understanding SNAS is the first step in reclaiming control over your health. It’s your body, and it’s important to know how it works, even when things go a bit awry. Armed with this knowledge, you can work alongside healthcare professionals to manage your symptoms and live a healthier, happier life.

Behind the Scenes: The Science of Nickel Allergy

Nickel allergy, much like any other allergy, is a response our bodies mount when they mistakenly identify nickel as a threat. Imagine it like this: your body’s defense system, also known as your immune system, usually works as an elite team that protects you from harmful invaders like viruses and bacteria. But, when it comes to nickel, things take a confusing turn.

In the case of nickel allergy, your immune system is like a guard that mistakes a friendly visitor for an enemy spy. The result? It overreacts and triggers a state of emergency, sounding the alarm throughout your body. This overreaction is what leads to the allergy symptoms.

The immune response releases chemicals like histamines, which are usually there to help fight off harmful invaders. But, in this case, they can cause a chain reaction of discomfort. This is when you start to experience the telltale signs of a nickel allergy, which might include redness, itching, and swelling where your skin came into contact with nickel.

In some cases, if you’re sensitive to nickel and you eat or drink something containing the metal, your immune system’s response can affect your entire body, leading to widespread symptoms. This is Systemic Nickel Allergy Syndrome (SNAS), a condition that can seem overwhelming but is manageable once properly identified.

Remember, even though your immune system may be overreacting, it’s just trying to protect you. The key is learning to live in harmony with your body, and that begins with understanding what’s happening behind the scenes when you’re dealing with a nickel allergy.

SNAS and You: Personalizing the Symptoms

Each person’s experience with Systemic Nickel Allergy Syndrome (SNAS) is unique, as individual as your fingerprint. What does this mean for you? Well, it indicates that your symptoms might not look exactly like those of your friend, neighbor, or that person you read about online. You see, your body, in its own unique way, expresses how it responds to nickel.

For some, the response might seem like a mild skin irritation — a little redness here, a bit of itching there, perhaps a rash that appears seemingly out of nowhere. For others, the reaction could be more severe, with painful, inflamed blisters or hives marking the areas where skin has come into contact with nickel.

The story doesn’t stop at skin symptoms. Remember, SNAS is systemic. That’s a fancy way of saying it can affect your whole body. You might experience a range of puzzling symptoms that you wouldn’t normally connect to an allergy. This could include abdominal pain, nausea, or even persistent fatigue.

Imagine trying to solve a mystery where the clues don’t seem to fit together. That’s what it can feel like when you’re dealing with SNAS. But the good news is that once you’ve identified nickel as the culprit behind your symptoms, you’re well on your way to reclaiming your health.

So, pay close attention to your body’s signals, because your personal journey with SNAS will be just that – personal. And remember, the more you understand your symptoms, the better equipped you’ll be to manage your condition effectively.

Allergy Alarm: Recognizing the Warning Signs of Nickel Allergy

Tuning into your body is essential when dealing with a nickel allergy. It’s like being a detective on the hunt for clues about what’s causing your discomfort. The signs of a nickel allergy can manifest in various ways, and learning to recognize these warning signs can help you take action early and avoid potential triggers.

The most common signal of nickel allergy is a skin reaction, often occurring in areas that have been in contact with nickel-containing items. This could be anywhere from your earlobes, where you might wear earrings, to your wrist, where you might wear a watch or a bracelet. If you see redness, itching, swelling, or rash in these areas, you might be dealing with a nickel allergy.

Sometimes, the skin reaction isn’t just a simple rash. It could develop into eczema or even blisters filled with fluid. These more severe symptoms usually occur after prolonged or frequent exposure to nickel.

Remember, nickel allergy doesn’t stop at skin reactions. It can present more like a mystery novel than a clear-cut case. Some people might experience symptoms that don’t seem related to an allergy at all, such as digestive problems, chronic fatigue, or recurring headaches. That’s because, with Systemic Nickel Allergy Syndrome (SNAS), your whole body can react to nickel, not just your skin.

Listen to your body. If you notice a pattern of these symptoms flaring up after coming into contact with potential sources of nickel or consuming nickel-rich foods, it might be time to discuss with your healthcare provider. After all, recognizing the warning signs is your first step towards managing a nickel allergy effectively.

Detective Work: Diagnosing SNAS and Nickel Allergy

Unraveling the mystery of nickel allergy and SNAS involves a good deal of detective work. It’s not just about identifying the signs but also connecting the dots to identify the underlying cause. When you suspect a nickel allergy, the first step is to discuss your symptoms with your healthcare provider. But, how does the diagnosis happen? Let’s walk through it.

Patch testing is the primary tool doctors use to diagnose a nickel allergy. During a patch test, small amounts of potential allergens, including nickel, are applied to your skin using tiny patches. These patches remain on your skin for a couple of days. If you’re allergic to nickel, your skin will react to the patch, leading to redness and itching at the test site.

However, diagnosing SNAS is a bit more complex. SNAS involves systemic reactions to nickel, which means it can cause a wide variety of symptoms that aren’t solely linked to skin contact. So, healthcare providers must pay attention to more than just skin reactions. They need to take a careful medical history, look at your symptoms, and often will perform an oral nickel challenge. This is where you consume a controlled amount of nickel, and your healthcare provider observes for reactions.

Another diagnostic tool is a low-nickel diet. If your symptoms improve while on this diet, it might suggest you have SNAS. Your doctor may also recommend blood tests to check for specific markers that could indicate an allergy.

In this detective story, you are your best advocate. Keeping a detailed symptom diary can be incredibly helpful in diagnosis. By recording when and where your symptoms occur, along with what you’ve eaten or what items you’ve been in contact with, you can provide crucial clues to your healthcare provider. The more information you provide, the better chance of getting an accurate diagnosis, bringing you one step closer to effective management of SNAS or nickel allergy.

Turning the Corner: Effective Treatment Strategies for Nickel Allergy and SNAS

The tables can be turned on nickel allergy and SNAS with an effective treatment strategy. No need to feel overwhelmed, there are several methods to tackle these conditions and regain control over your health.

First and foremost, prevention is key, and that means avoiding nickel as much as possible. Granted, that’s a tough task, as nickel is ubiquitous in our environment. It will require you to be vigilant and proactive. You may need to replace some clothing items, kitchen utensils, or even work tools. Always keep an eye out for ‘nickel-free’ labels when shopping for new items. A neat trick is to use clear nail polish on small items to create a barrier between the nickel and your skin.

Now, in addition to these measures, consider using Dimethylglyoxime (DMG) tests for nickel. Here’s an affiliate link where you can order DMG to test items for the presence of nickel. When you apply this liquid to a surface that releases over 10 ppm of nickel, it turns pink. However, this test does have limitations. If it shows a positive result, there’s a 98% certainty that the surface indeed releases more than 10 ppm of nickel. However, a negative outcome isn’t as trustworthy, with a 40% likelihood of it being incorrect. This uncertainty is something to keep in mind when testing metallic objects that regularly come into contact with your skin. [PMID: 20536475]

Frequent sauna use may help with the excretion of excess nickel. [PMID: 21057782] Consider investing in an Infra-Red Sauna Blanket (Amazon Affiliate Link).

Medications can also play a role in managing your symptoms. Topical corticosteroids can help to control skin reactions, while oral corticosteroids or antihistamines might be used for more severe symptoms or systemic reactions.

Remember, everyone’s body reacts differently, and there’s no one-size-fits-all treatment. It may take some time to find what works best for you. It’s crucial to work closely with your healthcare provider throughout this process. Be patient, proactive, and positive. Turning the tables on nickel allergy and SNAS is entirely possible, paving the way to improved well-being and quality of life.

A Low Nickel Diet Is Key For Systemic Nickel Allergies

For SNAS, it’s also about what you eat. Adopting a low-nickel diet can be very helpful. Certain foods like whole wheat, oats, nuts, beans, and shellfish, tend to be high in nickel and might need to be limited or avoided. A nutritionist can guide you in creating a balanced and nutritious low-nickel diet.

The source of the data in the tables below is an app called “Nickel Navigator,” which references nickel data from individual studies listing food from around the world. This data is frustratingly unreliable and inadequate for anyone trying to control their nickel intake at a very low level, however, this is the best data available at this time.

It’s important to realize that the quantity of nickel in any food is dependent on the soil where it was grown and the animal feed that was used. Food processing is another factor. For example, pineapple is canned in zinc-lined cans which may have nickel as a contaminant in the zinc, causing the food to be extremely high in nickel. The pots and pans used to prepare foods may also leach appreciable amounts of nickel.

High-Nickel Foods that Should Be Avoided:

High Nickel Food ItemsNickel Content per Serving (mcg)
Oats (1 cup, cooked)85 +/- 25 mcg
Whole wheat bread (1 slice)15 mcg
Lentils (1 cup, cooked)28-70 mcg
Chickpeas (1 cup, cooked)21-34 mcg or more
Almonds (1 oz.)27 mcg (wide variation)
Cashews (1 oz.)171 +/- 42 mcg
Soybeans (1 oz, dried)122 +/-73 mcg
Black Beans (3 oz canned)112 mcg
Canned pineapple (1 cup)14 +/-10 mcg, but sometimes 119
Spinach (3 ounce)1 to 51 mcg
Chocolate (1 oz.)37 mcg, but may be extremely high.
Low-Nickel Food ItemsNickel Content per Serving (mcg)
Egg (1 large)1.5 mcg
Poultry (4 oz, cooked)0.4 mcg (no US data)
White rice (1 cup, cooked)5.4 mcg (unreliable)
Mushrooms (3 ounces)0.3 mcg, but possibly very high
Beef (3 oz, cooked)2.6 mcg
Cheese (1 oz)2 mcg
Cabbage (1 cup, cooked)2 mcg, but possibly very high nickel
Cucumber (1 medium)3.5 mcg
Fish (3 oz, cooked)8 mcg, with very high variability
Tomatoes (1 medium)2 mcg (Wide variation, 10-60 for Canned Tomato)
Apples (1 medium)2 mcg
Orange (1 medium)2 +/- 2 mcg
Bananas (1 medium)6.2 +/- 5 mcg
Carrots (1 cup, cooked)2 mcg (up to 40 mcg)
Potatoes (1 medium)16 mcg for US, up to 36
Broccoli (1 cup, cooked)8 mcg, possibly very high
Strawberries (1 cup)8 mcg, wide variation, possibly very high
Whole milk (1 cup)< 1 mcg in the US

Tip: Drink Your Water With Food

Whatever nickel is present in water will be absorbed into the system much more quickly than when you drink water with food. Researchers looked at how eating and fasting affect nickel absorption from water. In one study, eight men not allergic to nickel were given nickel-infused water and scrambled eggs at different times. Nickel levels in the blood spiked 13 times higher when water was drunk before eating. This spike was smaller and delayed when the water and eggs were consumed together. Researchers concluded that eating and the speed of stomach emptying significantly impact nickel absorption. [PMID: 9882593]

The average concentration of nickel in drinking water in the US is between 2 and 4.3 ppb and it is usually below 10 ppb according to an ATSDR report. The key is knowing that 1 ppb (part per billion) is equivalent to 1 microgram per liter. Call your state water authority or University Extension office to begin searching for the nickel quantities in your local water.

Or, Remove the Nickel From Your Water

Another option is to just get rid of whatever nickel might be present in your water. Two popular methods to remove nickel and other heavy metals from water:

  1. Reverse Osmosis (affiliate link): This involves forcing the water through a semipermeable membrane that blocks the passage of nickel ions while allowing water molecules to pass through. This method is commonly used in home and commercial water filtration systems.
  2. Activated Carbon Filtration (affiliate link): Activated carbon filters can effectively remove nickel and other contaminants from water. This process works through adsorption, where the nickel ions are attracted to and stick to the surface of the activated carbon particles.

Everyday Tips to Avoid Nickel Exposure

Avoiding nickel entirely can be challenging, but there are many strategies you can implement to significantly reduce your exposure. Here are some everyday tips to help you live in harmony with your nickel allergy:

  1. Jewelry Savvy: Choose jewelry made of materials like surgical-grade stainless steel, titanium, 18 karat gold, or platinum. These materials either don’t contain nickel or have such a low amount that it generally doesn’t cause reactions.
  2. Clothing Choices: Watch out for nickel in unexpected places like the metal buttons on jeans or fasteners on clothing. Choose clothing with plastic fasteners, or create a barrier between your skin and the metal using fabric or a nickel-guard product.
  3. Smart Shopping: Look for products labeled ‘nickel-free’ when buying items like eyeglasses, watches, hair accessories, or belt buckles.
  4. Diet Decisions: While it’s not necessary for most people with nickel allergy to avoid foods containing nickel, those with systemic nickel allergy syndrome (SNAS) may benefit from a low-nickel diet. Consult with a dietitian or healthcare provider to ensure you’re maintaining a balanced diet while avoiding high-nickel foods.
  5. Home Improvements: If possible, choose nickel-free fixtures and fittings in your home, particularly in the bathroom and kitchen where frequent contact with water can cause nickel to leach out.
  6. Tech Tools: Be aware that mobile phones, laptops, and tablets often contain nickel. Consider using a cover or case to limit skin contact.

Remember, everyone’s sensitivity to nickel can be different. What works well for one person may not work as well for another. It’s all about finding the balance that allows you to live comfortably without triggering allergic reactions. Your healthcare provider or an allergist can provide personalized advice based on your level of sensitivity.

Embrace the Future: Ongoing Research and Hope for SNAS and Nickel Allergy Sufferers

Despite the challenges that come with living with systemic nickel allergy syndrome (SNAS) and nickel allergy, it’s crucial to remember that there’s ongoing research and continual development in understanding and managing these conditions. Scientists around the globe are working tirelessly, not only to find better ways to treat and manage nickel allergies but also to understand the deeper mechanisms behind them.

Already, the rise of ‘nickel-free’ alternatives in everyday items is a testament to the changes that awareness and understanding can bring about. Plus, each new study and every piece of research adds another piece to the puzzle, increasing our collective knowledge about these conditions and bringing us closer to a future where living with SNAS or a nickel allergy is less burdensome.

In the meantime, by taking control of your environment, understanding what triggers your symptoms, and working closely with your healthcare provider, you can lead a comfortable and fulfilling life. The journey may not always be easy, but it’s worth taking steps towards a future where nickel allergies and SNAS are well-managed and less impactful on daily life. Hold onto hope, embrace the future, and know that every day brings us closer to more effective solutions for SNAS and nickel allergy sufferers.

You will also want to check out the Rebelytics article on the management of nickel allergy.

The Unexpected Anti-Aging Warrior: How Metformin Could Extend Your Healthspan

June 26, 2023

Metformin is a medication that has been used for over 60 years to treat type 2 diabetes. Recently, it’s been noticed that beyond controlling blood sugar levels, this drug might have additional health benefits – including possibly helping people live longer and healthier lives.

Scientists have been studying animals like mice and a type of worm called C. elegans, and they found that metformin can help these creatures stay healthy longer. These promising results have led to new studies in people to see if metformin could have similar “anti-aging” benefits for us.

Longer Lifespan is Still A Maybe, But Healthspan Is A Definite YES

Two major studies, called MILES and TAME, are trying to figure out if metformin can help humans live longer, healthier lives. Early results from the MILES study suggest that metformin could influence our bodies at the genetic level in ways that might slow aging. However, it’s not yet clear if metformin would have the same benefits in people who don’t already have a disease like diabetes.

Even though metformin has been around for a long time, we still don’t fully understand how it works on a cellular level. When looking at all the research that’s been done, it’s clear that metformin can help improve “healthspan” – that is, the length of time a person stays healthy, not just how long they live. It does this by helping to manage diabetes, heart disease, mental decline, and even some cancers, which in turn can lead to a longer, healthier life.

But as far as actually extending lifespan – making people live significantly longer – the evidence is not as clear. The key point seems to be that metformin helps to prevent or manage disease, which then leads to a healthier, and potentially longer, life.

In conclusion, the potential “anti-aging” effects of metformin seem to come from its ability to control blood sugar levels, improve insulin sensitivity, reduce stress on the body at the cellular level, and protect the blood vessels. But more research is needed to fully understand how metformin might help us stay healthy as we age. [PMC8374068]

The History of Metformin

Metformin, a key medication for type 2 diabetes, traces its roots to the French lilac, or Galega officinalis. This plant was traditionally used to alleviate symptoms we now know to be associated with diabetes. Its active compound, galegine, was effective but also toxic. In response, scientists in the 1920s created metformin, a safer derivative of galegine. Since its introduction in France in the 1950s, metformin has become a worldwide staple in diabetes treatment, demonstrating how nature can inspire modern medicine.

The most common side effects of metformin are digestive problems, such as abdominal pain, bloating, and nausea. These side effects can often be managed and only rarely lead to people needing to switch to a different drug. Metformin is considered safe for almost all users. The major exception is that anyone with severe kidney or liver issues must avoid taking metformin. This is due to a rare but serious side effect called lactic acidosis, which can occur in these patients. By taking this precaution, the risk of lactic acidosis is effectively minimized.

A major caution for anyone taking metformin is the side effect of B12 deficiency. Some studies have reported that prolonged use of metformin could result in vitamin B12 deficiency, which affects between 6 to 30% of users. Therefore, it’s critical that anyone taking metformin have B12 supplementation and/or B12 labs. These can be ordered easily from LabCorp or Quest through our affiliate link for B12 Labs. Vitamin B12 and Folate Blood Test or Wellness Panel With Vitamin B12, D, Folate, and Magnesium. Click on the “Labs” link on the top bar above this article for a more extensive list of labs.

Given how widely metformin is used and its range of health benefits, there’s a growing interest in whether it might have anti-aging properties. When we say “anti-aging,” we mean that it helps prevent or treat diseases related to aging, allowing people to stay healthy and free of serious illness for a longer portion of their life.

There’s some debate about how to define and measure this concept of “healthspan,” but for our purposes, we’re talking about reducing the risk of serious illness, which could, in turn, increase overall lifespan.

On the bright side, metformin often leads to weight loss, helps manage blood sugar levels, and doesn’t cause low blood sugar. It’s also been found to be effective in preventing the onset of diabetes in people who are at risk. [PMC1282458] The widespread use of metformin for diabetes really took off after a 20-year study from the UK showed that it had benefits for heart health. Since then, it’s become clear that metformin doesn’t just work in the liver (as was initially thought), but also has important effects in the gut.

Metformin Benefits Beyond Blood Sugar

As a trusted and widely-used treatment for diabetes, metformin has made a name for itself in managing blood sugar levels and enhancing heart health. However, the potential benefits of metformin extend beyond these well-established applications.

In recent years, metformin’s usage has expanded to include the treatment of polycystic ovary syndrome (PCOS), a common condition in women of reproductive age. Its use has also been tested in the context of preeclampsia, a dangerous complication that can occur during pregnancy.

Additionally, metformin is being studied for its potential benefits in the realm of oncology. Some research suggests that it may have anti-cancer properties, opening up another fascinating avenue of use for this versatile drug.

The benefits of metformin might not stop at chronic conditions. Preliminary studies suggest it may also have a role to play in the treatment of infectious diseases. It’s even being looked at in the context of rheumatoid arthritis, a debilitating autoimmune condition.

Summary

With its multitude of potential applications, metformin is garnering attention as the “aspirin of the 21st century.” Its potential to extend healthspan—the period of life spent in good health—could make it a key player in the quest for healthier, longer lives. In the end, while much research is still needed, metformin’s potential as a healthspan extender is promising. As we continue to unlock its full potential, metformin could prove to be a versatile ally in our health toolkit.

Unraveling Your Mystery Illness: Is Time To Test for Metal Exposure?

June 24, 2023


While many of us might associate metal toxicity with industry-related incidents or high-profile cases like mercury poisoning from contaminated fish, the reality is more nuanced. Exposure to heavy metals can occur in everyday life, leading to a myriad of health issues, including chronic fatigue triggers, that can be perplexing and difficult to diagnose. This article aims to shed light on the often unseen threat of metal toxicities, their potential impacts on our health, specifically chronic fatigue, and how to identify them. We’ll also provide resources for testing for heavy metal exposure, which is a critical step toward finding better health.

The Mystery Illness Connection

Diagnosing metal-related health issues can be complex due to overlapping symptoms with other conditions. For instance, chronic fatigue, a symptom common in conditions like depression, anemia, or thyroid problems, is also a sign of lead and mercury toxicity. Similarly, skin rashes, often associated with allergic reactions, can result from nickel or chromium exposure.

There have been numerous cases where individuals suffered from unexplained symptoms for years before discovering their ailments were due to metal toxicity. In one case, a woman who experienced chronic fatigue and memory problems was found to have high levels of mercury from consuming a diet high in fish. In another case, a man working in battery manufacturing was diagnosed with lead poisoning after suffering from prolonged abdominal pain and irritability.

Toxins Bioaccumulate

Metal toxicities occur when heavy metals, due to environmental exposure accumulate to harmful levels. This accumulation can come from the air we breathe, the water we drink, the food we eat, or even the occupation we work in. Tatoo inks contain various levels of metals that may add up. [PMC9846827] Rice, wine, and water are sources of arsenic in foods. [PMC5743452]

Bioaccumulation refers to the gradual accumulation of substances, like pesticides, chemicals, or heavy metals, within an person’s body. This happens when a person absorbs a substance faster than it can be metabolized or excreted.

Eating large species of fish such as tuna and shark can pose a risk because of “biomagnification” of mercury. Biomagnification refers to the increase in the concentration of a substance as it moves up the food chain, ultimately leading to higher levels within animals higher on the food chain.

Metal Exposure Through Tatoo Inks?

There’s no question that tatoos can be beautiful, but researchers have raised the question of how much exposure to metals there might be through tatoo ink–especially when tatoos are extensive.

Technically, the FDA regulates tatoo inks and determines the “safe” levels of metals that inks may contain. The problem is that a safe level for most people may not be a safe level for everyone. One example is nickel sensitivity where people of northern European descent may not even be able to tolerate the tiny amounts of nickel in foods [PMC4406458]. Then, there is the issue that each metal on its own may be safe, but the combinations, quantities and variability in ink quality and ink purity have never been studied.

When researchers have scratched the surface of this question, they have found a great deal of variability in the levels of various metals in commercially available inks depending on the color and the brand. PMC9846827

The Most Common Metals and Their Effects on Health

Various metals have different effects on our bodies, depending on their nature and the extent of exposure. Lead, for instance, can cause neurological and cognitive problems, especially in children. Mercury can affect the nervous system, leading to mood swings, tremors, and muscle weakness. Other metals such as Arsenic, Cadmium, Aluminum, Nickel, Copper, Chromium, and Iron, have a wide range of effects, from skin rashes and stomach upset to more severe issues such as lung and kidney damage or diseases of the bone and brain.

Symptoms can vary widely based on numerous factors, including the person’s overall health, how long they’ve been exposed, and the specific type(s) of metal involved. It’s important to contact a healthcare provider if you suspect metal toxicity. Some symptoms might overlap with other conditions, and accurate diagnosis requires professional medical evaluation and tests.

MetalCommon Symptoms
LeadAbdominal pain, constipation, fatigue, headache, memory problems, irritability, loss of developmental skills in children
MercuryMood swings, nervousness, irritability, insomnia, headaches, abnormal sensations, muscle twitching, tremors, weakness, muscle atrophy
ArsenicSkin changes (darkening or discoloration), white lines on nails (Mees’ lines), numbness, pain in hands and feet, nausea, vomiting, diarrhea, muscle weakness
CadmiumChest pain, cough, fever, muscle pain, sense of smell loss, shortness of breath, wheezing
AluminumBone diseases, brain diseases, iron deficiency anemia
NickelSkin rash, itching, difficulty breathing, chest pain, fast heartbeat, weakness
CopperMetallic taste in the mouth, vomiting, diarrhea, stomach cramps, nausea, fever, blood in urine
ChromiumLung problems, skin rash, upset stomach, kidney and liver damage, lung cancer, alteration of genetic material
Iron (overdose)Stomach upset, constipation, nausea, abdominal pain, fainting, dizziness, weakness
This table contains only a subset of heavy metals.

How Heavy Metals Poison the Mitochondria

Heavy metals, such as lead, mercury, and cadmium, have the potential to poison the mitochondria, the cellular powerhouses responsible for all energy production in every cell of the body.

  • Firstly, heavy metals can increase the production of “free radicals” within cells. These are highly reactive molecules that can damage cellular structures, including mitochondria. This oxidative stress caused by heavy metals can lead to mitochondrial dysfunction.
  • Heavy metals can also directly damage the mitochondrial membrane. This damage disrupts the transport of electrons during oxidative phosphorylation, impairing ATP production and overall energy metabolism.
  • Also, certain heavy metals, such as arsenic and lead, can interfere with the enzymes involved in mitochondrial respiration and ATP synthesis. By interfering with these enzymes, heavy metals disrupt the normal functioning of mitochondria.
  • Heavy metals can disturb calcium channels within cells. Calcium is a critical regulator of mitochondrial function, including ATP production and programmed cell death (apoptosis). Imbalances in calcium levels due to heavy metal exposure can impair mitochondrial function and compromise cell survival. This shows up as problems with muscle contraction, neurotransmitter release, gene expression, and cell signaling.

One of the most challenging aspects of health problems associated with mitochondrial damage is their lack of specificity. Mitochondria create almost all the energy in every cell of every organ system of the body, so when they aren’t working because of heavy metal damage, there are widespread consequences. The symptoms of mitochondrial damage vary greatly, ranging from fatigue, muscle weakness, and cognitive impairment to gastrointestinal disturbances, cardiac abnormalities, and neurological disorders.

This non-specificity stems from the fact that mitochondria are present in nearly all cell types, and their dysfunction can disrupt vital cellular processes, leading to diverse and sometimes overlapping health problems across multiple organ systems. This is why testing for metal toxicities makes so much sense when a person is dealing with long-term, chronic, multisystem mystery illnesses.

Ordering Lab Tests For Heavy Metals

The symptoms associated with metal toxicities overlap with those of other medical conditions, making diagnosis challenging. Common symptoms might include stomach upset, skin rashes, neurological problems, muscle weakness, and more. Time-constricted healthcare providers are often so busy thinking about the more common causes of all these symptoms that they may not consider the possibility of testing for heavy metals. Even worse, because complaints are so widespread across different body systems, physicians may even suspect these symptoms are the result of psychiatric problems.

So, if chronic illness is a part of daily life, it may help to rule out heavy metal toxicity as a potential cause. Tests that detect a broad range of potential metal toxicities can easily be ordered online through these affiliate links:

Prevention and Treatment

Reducing exposure to heavy metals is crucial. This could involve measures like ensuring safe drinking water, reducing the use of products containing heavy metals, or wearing personal protective equipment in jobs with high metal exposure risk.

As for treatment, it usually involves removing the source of exposure and sometimes using medications that can bind to the metals in your body, a process called chelation. However, every situation is unique and requires personalized medical advice.

Conclusion

Understanding the potential dangers of metal toxicities and their link to some mystery illnesses highlights how important it is to be aware and proactive about our health. What we eat and drink and what we are exposed to in our environment deeply impact our well-being, and seemingly inexplicable symptoms might have more tangible causes than we think.

Pushing the Limit: How Intense Workouts Turbocharge Your Cortisol Levels

June 10, 2023


For athletes who engage in intensive training, elevated cortisol can be a problem. A study sought to provide some insights into how different exercise intensities impact cortisol response. Twelve active, moderately trained men performed exercises at 60% and 80% of their maximal oxygen uptake (VO2max), and their cortisol levels were assessed before and after each session. The study found that both 60% and 80% intensity exercises significantly increased cortisol levels. Therefore, the study suggests that moderate to high-intensity exercise can stimulate an activation of the hypothalamic-pituitary-adrenal (HPA) axis and an increase in cortisol levels. These findings are important for athletes to consider, especially those engaged in high-intensity training, for effective management of their cortisol levels. [PMID: 18787373]

Understanding Insulin Resistance in PCOS: A Comprehensive Guide

June 1, 2023

As someone with PCOS, it’s vital to understand how insulin resistance may play a role in your condition. The more you understand about this, the better you can work with your medical providers and the more control you can have over your health.

Polycystic Ovary Syndrome (PCOS) is a complex hormonal disorder that presents in different ways among different women. The common thread is an imbalance in reproductive hormones, which can lead to irregular menstrual periods and other symptoms such as excess hair growth and acne.

While insulin resistance is a common feature in PCOS, it’s not present in all cases. In fact, about 20-30% of women with PCOS do not have insulin resistance. This variation might be due to differences in the specific hormonal and metabolic disturbances, genetic factors, and lifestyle factors such as diet and physical activity level.

It’s also possible for a woman to have PCOS without being overweight or obese, a condition often referred to as “Lean PCOS”. Even though obesity and insulin resistance often go hand in hand, lean women with PCOS might still have an imbalance in their reproductive hormones leading to the typical PCOS symptoms, but not exhibit insulin resistance.

What is Insulin Resistance?

Insulin is a hormone produced by your pancreas. Its main job is to regulate blood sugar levels by helping your cells absorb glucose. Insulin resistance happens when your body’s cells don’t respond well to insulin, leading to high levels of both insulin and glucose in your blood. It’s a key factor in the development of type 2 diabetes and it is often associated with PCOS.


Understanding Insulin and Its Function

Insulin is a vital hormone, produced by beta cells in the pancreas. After you consume food, carbohydrates are broken down into glucose, a simple sugar that is the body’s primary source of energy. The increase in glucose triggers your pancreas to produce and release insulin. This hormone acts as a key, unlocking your body’s cells so that glucose can enter them and provide energy. It’s a crucial part of maintaining a healthy energy balance in your body.

Insulin Resistance: An Impaired Response

Insulin resistance, on the other hand, disrupts this process. It is a condition where your body’s cells become less responsive to the effects of insulin. Think of it as the cell’s lock being rusty – the key (insulin) doesn’t work as well as it should, and less glucose can enter the cells.

This causes two major problems. Firstly, because glucose can’t enter the cells effectively, it builds up in the blood, leading to high blood sugar levels. Secondly, in response to this high blood sugar, the pancreas produces more insulin in an attempt to encourage cells to take in more glucose. This leads to an excess of insulin in the blood.

Over time, the pancreas may struggle to keep up with this increased demand for insulin production. This can lead to the development of type 2 diabetes, a condition where the body doesn’t produce enough insulin or the body’s cells ignore insulin.

Insulin Resistance and PCOS: The Connection

Insulin resistance is often linked to Polycystic Ovary Syndrome (PCOS), a hormonal disorder common among women of reproductive age. Women with PCOS often produce more insulin than women without the disorder due to the presence of insulin resistance. This excess insulin stimulates the ovaries to produce more androgens (like testosterone), which can interfere with ovulation, cause acne and hirsutism (excessive hair growth), and lead to weight gain – common symptoms of PCOS.

Insulin resistance doesn’t just impact glucose and insulin levels; it also plays a significant role in lipid metabolism, contributing to an abnormal lipid profile seen in many women with PCOS. This includes higher levels of triglycerides and lower levels of high-density lipoprotein (HDL), the “good” cholesterol.

Understanding the interplay between insulin resistance and PCOS is crucial for managing the syndrome effectively. Addressing insulin resistance through lifestyle modifications and, if necessary, medication, can help manage the symptoms of PCOS, reduce the risk of complications, and improve overall health.

Symptoms of Insulin Resistance in PCOS

If you have insulin resistance, you might experience a few distinct symptoms. This includes weight gain (especially around the waist), dark patches of skin (acanthosis nigricans), and feeling tired after meals. It’s worth noting that these symptoms often overlap with those of PCOS, such as irregular periods, acne, and difficulty losing weight.

Lab Tests for Detecting Insulin Resistance

If you suspect you have insulin resistance, there are several lab tests your healthcare provider might recommend. These could include a fasting insulin level, HOMA-IR, or a glucose tolerance test. Each of these tests provides different information about your body’s insulin sensitivity, so they’re often used together to provide a comprehensive picture.

Laboratory tests used to detect insulin resistance:

  1. Fasting Insulin Level: As the name suggests, this test requires the patient to fast (usually overnight) before a blood sample is drawn. This sample is then used to measure the level of insulin in the blood. Elevated fasting insulin levels can be an early indicator of insulin resistance, as the body may need to produce more insulin to effectively lower blood glucose levels.
  2. Homeostatic Model Assessment for Insulin Resistance (HOMA-IR): This test estimates insulin resistance by using a mathematical model that incorporates both fasting glucose and insulin levels. Specifically, it calculates the ratio of fasting insulin to fasting glucose, as this ratio can provide insight into how hard the body has to work to maintain proper blood glucose levels. A higher HOMA-IR score usually indicates greater insulin resistance.
  3. Glucose Tolerance Test (GTT): This test evaluates how quickly the body can clear glucose from the bloodstream. After fasting, the patient consumes a solution with a high concentration of glucose, and blood samples are taken at regular intervals for several hours to measure the glucose and sometimes insulin levels. If the glucose levels remain high for a prolonged period, it suggests the body is not effectively using insulin to lower blood glucose levels, which is a sign of insulin resistance.
  4. Hemoglobin A1c (HbA1c): Although this test isn’t directly used to detect insulin resistance, it is an important marker for long-term glucose control and is often used in diagnosing and monitoring diabetes. HbA1c measures the percentage of hemoglobin – a protein in red blood cells – that is coated with sugar, reflecting average blood glucose levels over the past two to three months. Higher levels of HbA1c can suggest problems with insulin sensitivity.
  5. Lipid Profile: People with insulin resistance often have alterations in their lipid profile, like increased triglyceride levels and decreased HDL cholesterol (“good cholesterol”). Thus, a comprehensive lipid profile can also be helpful in assessing insulin resistance.
  6. C-Peptide Test: C-peptide is produced in the body along with insulin. This test measures the level of c-peptide in the blood, which indirectly indicates the amount of insulin produced by the body. Higher c-peptide levels may suggest more insulin is being produced due to insulin resistance.

These tests aren’t always definitive, and a single test alone may not sufficient to diagnose insulin resistance. They are all pieces of a larger puzzle, and healthcare providers often use them together, along with physical examination and consideration of individual risk factors and symptoms, to provide a comprehensive assessment of a patient’s insulin sensitivity.

Understanding Body Types and Insulin Resistance

Lean PCOS refers to women who are diagnosed with Polycystic Ovary Syndrome but who are not overweight or obese. Contrary to popular belief, not all women with PCOS are overweight or obese. Lean PCOS can be difficult to diagnose as it does not present the typical PCOS picture that includes weight gain, particularly around the abdomen. Nonetheless, women with lean PCOS still experience hormonal imbalances and other symptoms characteristic of PCOS, such as irregular periods, elevated levels of androgens, and polycystic ovaries identified on ultrasound.

Even though they maintain a normal weight, some women with Lean PCOS can still have insulin resistance. Studies have found that insulin resistance in PCOS isn’t strictly associated with excess weight, meaning that even lean women with PCOS can be affected. Insulin resistance in these cases might arise due to factors like genetic predisposition, inflammation, or increased production of insulin by the pancreas.

On the flip side, overweight or obese women with PCOS are more likely to have insulin resistance. Extra weight, particularly if it’s carried in the abdominal area, decreases the body’s sensitivity to insulin, leading to insulin resistance. This occurs because visceral fat, the fat that surrounds the organs in the belly, releases various substances that negatively impact insulin signaling.

Regardless of body type, insulin resistance in women with PCOS can lead to a host of health complications. These include an elevated risk of developing type 2 diabetes, metabolic syndrome, cardiovascular diseases, and fertility issues.

Lifestyle modifications are crucial for managing both PCOS and insulin resistance. This includes regular exercise and a balanced, nutrient-rich diet. For some women, weight loss, if they are overweight, can significantly enhance insulin sensitivity and alleviate PCOS symptoms. Yet, even in cases of Lean PCOS, lifestyle changes can contribute to better insulin sensitivity and symptom management.

Lifestyle Implications and Modifications

Understanding your insulin resistance status is crucial as it directly impacts the lifestyle choices you’ll need to make. Research suggests that specific dietary modifications can help manage insulin resistance. One example is adopting a low-carb diet, which focuses on reducing intake of carbohydrates, particularly simple sugars and refined carbs. These can cause abrupt spikes and crashes in blood sugar levels. Instead, a low-carb diet promotes the consumption of proteins, healthy fats, and complex carbohydrates that are high in fiber. This can help control blood sugar levels more effectively and lessen the amount of insulin your body needs to produce.

However, it’s important to mention that low-fat diets may not be a beneficial choice for those with insulin resistance. While it may seem intuitive to lower fat intake for weight loss or heart health, a diet too low in fats can lead to increased consumption of carbohydrates, particularly if those carbs are from processed or refined sources. This, in turn, can exacerbate insulin resistance by causing a significant rise and fall in blood sugar levels.

Another valuable dietary approach is the Mediterranean-style diet. This diet, rich in fruits, vegetables, whole grains, lean proteins, and healthy fats, like olive oil and fish, supports maintaining stable blood sugar levels, reducing inflammation, and providing a balanced nutrient intake to support overall health.

Exercise is another essential element in managing insulin resistance. Regular physical activity, such as cardiovascular exercise and strength training, can lower blood sugar levels and decrease the body’s insulin needs. Cardiovascular exercises, like brisk walking, running, cycling, or swimming, improve heart health and aid in regulating insulin levels. Strength training, like weight lifting or resistance exercises, helps build lean muscle mass, which in turn allows your body to store more glucose.

Stress management is also a critical factor in controlling insulin resistance. Techniques such as mindfulness, yoga, and simple breathing exercises can reduce stress levels and improve mental health, which indirectly benefit insulin sensitivity. For example, mindfulness involves focusing on the present moment without judgment, while yoga combines physical postures, breathing exercises, and meditation. Simple practices like deep breathing or guided breathwork also contribute to reducing stress and promoting relaxation.

Remember, adopting these lifestyle modifications is a personal journey and not a one-size-fits-all approach. It’s essential to consult with healthcare providers or a dietitian to create a personalized plan that fits your lifestyle, preferences, and medical needs.

Conclusion

So, it’s clear that insulin resistance is a crucial piece of the PCOS puzzle. It can dictate the symptoms you experience, the treatment strategies that will work best for you, and the lifestyle changes you’ll want to consider. Keep in mind that every woman with PCOS is unique. Understanding your body and how it relates to insulin resistance can be empowering and vital for your health journey. As always, consult with your healthcare provider for personalized advice. Stay strong, stay informed, and take care.

A Good Lab Test To Rule Out (Or Pick Up) Many Different Problems

February 9, 2023

customer panel

JBB MD Customer Panel includes CMP, CBC, Ferritin, Iron and TIBC, Lipid Panel, CRP, Magnesium RBC, Zinc RBC, Ceruloplasim, Vitamin B12, Folate, Homocysteine, TSH, and Free T4. 

A comprehensive metabolic panel is designed to pick up problems including diabetes, liver, and kidney problems. The Comprehensive Metabolic Panel (CMP-14) with eGFR is a group of 14 laboratory tests ordered to give information about the current status of your liver, kidneys, and electrolyte and acid/base balance.  The test gives the current status of your blood sugar and blood proteins also.

A Complete Blood Count (CBC) can tell you if your blood cells and immune system are in the normal range. A CBC helps your health professional check any symptoms, such as fatigue, weakness, or bruising, that you may have. A CBC helps your health professional diagnose anemia, infection, and other disorders.

The CBC test includes: WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelets, Neutrophils, Lymphs, Monocytes, Eos, Basos, Neutrophils (Absolute), Lymphs (Absolute), Monocytes(Absolute), Eos (Absolute), Basos (Absolute), Immature Granulocytes, Immature Grans (Abs)

Ferritin Serum Test is ordered to measure the amount of ferritin in the blood, which is an indicator of iron stores in the body. The test can indicate the presence and severity of iron deficiency or iron excess.

The Iron and TIBC Blood Test is ordered to assess the body’s ability to bind and transport iron in the blood. It is used when an iron deficiency or iron overload is suspected.

The Lipid Panel Blood Test evaluates cholesterol levels and may predict risk for coronary artery disease.

C Reactive Protein (hsCRP) can alert you to the level of inflammation in the body.  Inflammation is present in conditions such as arthritis, pelvic inflammatory disease, inflammatory bowel disease, and coronary artery disease. 

The Magnesium Blood Test, RBC is used to test for magnesium deficiency.

A Zinc Blood Test, RBC is a sensitive screening for zinc deficiency or overload.

A Ceruloplasmin Test is used to test for copper deficiency.

The Vitamin B12 Test is used to detect B12 deficiency as in pernicious anemia.

The Folate Serum Test is a test for Folic acid, a B vitamin that is needed for cell growth and metabolism.

The homocysteine blood test helps diagnose B12/folate deficiencies and to identify patients who may be at risk for cardiovascular disease.

Thyroid Stimulating Hormone (TSH) is used to screen adults for thyroid disorders.

Free T4 is the active form of thyroxine and may sometimes be a more accurate reflection of thyroid hormone function than TSH.

Is Your Adult Onset Diabetes Type 1? This Antibody Blood Test Might Tell the Answer

February 9, 2023

Zinc Transporter 8 Antibody

What is the difference between Type 1 and Type 2 Diabetes?

Type 1 diabetes usually develops in children and adults under 30. It is caused by the immune system attacking the islet cells of the pancreas that are responsible for making insulin. So, with type 1 diabetes, there isn’t enough insulin because our own immune system has killed off the insulin-producing cells. It usually happens suddenly with extreme thirst and weight loss followed by a trip to the doctor or the emergency room.

Type 2 diabetes usually presents in people over 30, but has become much more common in younger people with significant weight problems. Type 2 diabetes develops over the course of years or decades and involves insulin resistance as well as a reduction of insulin production over the course of time.

What is Latent autoimmune diabetes (LADA)?

Latent autoimmune diabetes (LADA) is a form of type diabetes type 1 that develops in adulthood.  LADA will usually progress more slowly than typical Type 1, and therefore is often misdiagnosed as type 2 diabetes.  Symptoms of latent autoimmune diabetes (LADA) are similar to what one would experience with other types of diabetes. It is the high blood sugar of diabetes that causes excessive thirst, drinking, and urination along with blurred vision.

Lab Tests For Type 1 Diabetes?

Antibody Tests for Type 1 Diabetes

The Zinc Transporter 8 Antibody Blood Test is useful for diagnosing autoimmune type 1 diabetes. This test will measure diabetes-related autoantibodies.  Although these autoantibodies do not induce type 1 diabetes, they do serve as indicators of the body’s immune response against its own cells that generate insulin.  

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C-Peptide Test for Type 1 Diabetes

The C-Peptide Serum Test is useful for monitoring insulin production. When a person’s pancreas produces insulin, it also creates an equal amount of C-Peptide. For those recently diagnosed with diabetes, testing the levels of this hormone is useful for determining if and when additional insulin therapy should begin.

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Reference

How to Test for Protein Malabsorption: The Indican Urine Test

December 31, 2022

indican urine test

An Indican Urine Test may detect malabsorption of proteins which may be a sign of a digestive or gastrointestinal issue. Possible conditions associated with abnormal test results range from autoimmune disease to dysbiosis and leaky gut. Restoring balance through dietary changes, appropriate supplementation if necessary, lifestyle changes, and stress management techniques will help bring those indican levels back into optimal ranges for better overall health.

What is Indican?

Through the process of digestion, bacteria residing in our intestines work to produce Indican – a metabolite derived from tryptophan. While most of it leaves our bodies during bowel movements, some is absorbed and processed by the liver and eventually released into our urine. Trace amounts are normally detected but higher than average concentrations may show a digestive or gastrointestinal issue.

Although an Indican Urine test cannot determine the specific digestive or gastrointestinal disorder, the results can still be used to point toward potential causes and treatments.

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What Can a High Indican Lab Tell You?

High indican levels could suggest underlying health problems such as auto-immune disease, celiac disease, or Crohn’s – but may also be due to gut infections, dysbiosis, and overgrowth of harmful bacteria in the gut. Other potential causes include IBS, liver problems, or low stomach acidity which lead to problems absorbing protein from food sources.

Indican and Excess Dietary Protein Intake

A high level of urinary indican isn’t always a cause for concern. In some cases, a high indican might just suggest an excessive intake of protein foods. This is likely to be the case if you are eating a lot of meat, eggs, dairy, or protein powder.

Who Should Consider an Indican Test?

Antacids and Medications for GERD Affect Protein Digestion

Protein requires stomach acid to fully break down into amino acids. Many people take over-the-counter antacids or prescribed medications for gastroesophageal reflux disease or “GERD”, which could affect the digestion of protein. If a person’s ability to break down protein is in question, the indican test could be of value.

Food Allergies

When a person does not adequately break down protein into the individual amino acids, these larger proteins have greater contact with the immune system and there is greater risk for food allergies to develop. (Reference) If you have a food allergy test that indicates multiple food allergies, it’s a good idea to investigate protein digestion as well as taking measures to address leaky gut.

Unexplained Digestive Upset Could Suggest Inadequate Protein Digestion

A person may order this test if they often experience digestive symptoms and want to investigate their digestive health further. Contact your doctor or healthcare provider if you have concerns or questions about your lab results.

Disclaimer:

Any person experiencing medical symptoms should consult with a medical provider. This article does not constitute medical advice.

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The BEST Choice for DNA Testing: Full Genome Sequencing From Nebula

August 20, 2022

Best Choice for Whole Genome DNA Tests

What’s the best choice for whole genome DNA tests? There is a single definite answer to that question!

Would You Rather Get 100% or 0.2% of Your DNA Data?

Most companies like Ancestry and 23andMe are set up to test only about 0.2% of your genome. That leaves behind a lot of useful information that you can find out with the 100% DNA sequencing Nebula offers. Choose Nebula Genomics DNA Testing and your DNA data will always be ready for you to reference as researchers make new genetic discoveries.

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Security

The second advantage of using the Nebula Genomics Company is its privacy technology. Nebula Genomics uses ultra-secure blockchain technology that separates your DNA data from all of your identifying information. Most other companies store your DNA data in traditional file formats that can easily be hacked.

Cost

NIH estimates the cost for generating the initial ‘draft’ human genome sequence is ~$300 million worldwide, of which NIH provided roughly 50-60%. Prices have dropped since then.

Nebula’s Pricing

Nebula’s Basic level scans your whole genome once for a price of $99. The Deep Level Whole Genome Sequencing from Nebula Genomics is priced at only $299 for the deep-level analysis. This analysis scans your DNA, not just once, but 30 times, so that you can be sure the results are right.

We checked the competition. Nebula offers by far the lowest cost in the industry among companies offering whole genome sequencing. There is also a subscription to the database, which is currently priced at $25 per month based on a quarterly subscription.

You will be able to download your DNA data. If your Nebula Subscription lapses, you will be able to re-subscribe at any time to re-analyze your results and take advantage of new discoveries in future years.

Turnaround Time

Crunching all that DNA data takes time even with Nebula’s high throughput technology. You should expect results in about 12 weeks.

Demonstration Video

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Vitamin D Blood Test-25-Hydroxy

May 19, 2022

Mountain Biking

Vitamin D is essential in the growth and formation of healthy bones and teeth. Without it, children can develop a bone-malformation condition known as rickets, and adults can develop osteomalacia, which is characterized by weakness, softness or fractures of the bones. Vitamin D also helps regulate levels of calcium, phosphorus and magnesium in the blood, and has been shown to influence the growth of other tissues in the body as well as the regulation of the immune system. Vitamin D deficiency has been implicated in the development of conditions such as cancer, heart disease‚ osteoporosis and multiple sclerosis.

The body gets vitamin D from two sources: dietary intake through foods and supplements (exogenous), and through production in the skin upon exposure to sunlight (endogenous). Although vitamin D is found naturally in only a few foods, in the United States, many products are supplemented with it, including milk, breakfast cereals and juices. Those at risk of vitamin D deficiency include individuals who are elderly; obese; have dark skin; are institutionalized, homebound or have limited sun exposure; have undergone gastric bypass surgery; and have conditions such as cystic fibrosis and Crohn’s disease that interfere with fat absorption.

The Vitamin D 25-Hydroxy Blood Test is often ordered for individuals that have symptoms of vitamin D deficiency. It may also be ordered before an individual begins osteoporosis drug therapy. Low levels may indicate a dietary deficiency, malabsorption or lack of exposure to sunlight.

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CD57 Blood Test- Part of the ReCODE Protocol

March 28, 2022

HNK1 (CD57) PROFILE BLOOD TEST

Why is CD57 Important in Evaluating Cognitive Problems?

The ReCODE protocol for recovery from cognitive decline has been uniquely successful in slowing and reversing cognitive decline because it searches for the widest range of potential sources of cognitive problems. Lyme disease is just one of those sources. Lyme disease has been found to be associated with the cognitive decline of some individuals. An active case of Lyme disease must receive adequate treatment in order to stop injury to the brain. Failure to address the inflammation associated with Lyme would be tragic, therefore testing is considered a critical part of the protocol.

What is the CD57 test for?

CD57 is used to monitor remission status in patients with chronic Lyme disease.

CD57 is a type of marker that is present on natural killer cells (NK) and T lymphocytes. In chronic diseases like Lyme disease, the number of CD57 NK cells has been shown to be below normal. It is believed that the lower the number of CD57 natural killer cells in the body, the more active the Lyme disease is, and the higher the amount, the closer a person is to remission.

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